LeadCare® Childhood Blood Lead Testing
ESA LeadCare Analyzer & Supplies

The LeadCare System is for the determination of lead in whole blood. When you test young patients for lead levels, you want fast, accurate, inexpensive results. You want the LeadCare system, a simple, foolproof way to perform blood lead measurements using a finger stick or venous sample. No more waiting days for expensive lab analyses. You get quantitative blood lead results equivalent to those reported by outside laboratories in just three minutes.

A LeadCare system analysis costs far less than you'd pay an outside laboratory, and it qualifies for reimbursement as a quantitative blood lead. You'll also cut your staff's result-tracking and administrative time. You'll save your patients days of possibly needless worry plus the time-consuming inconvenience and cost of a return visit. Blood lead measurement couldn't be easier.

LeadCare is easy and safe to use. The hand-held analyzer is portable and requires neither manual calibration nor refrigeration. Its unique gold electrode sensor contains no mercury or other toxic materials. The point-of-care LeadCare system was developed by ESA and Andcare with a grant from the CDC. It's the diagnostic tool which makes sense medically and economically.

 

  Fast! Easy as 1- 2- 3

STEP ONE
Step 1 - Draw a capillary

 Draw a capillary or venous blood sample using EDTA or heparin as anticoagulants.

STEP TWO
Step 2 - dispense two drops of blood

 Using the pipette provided with the kit, dispense 50 µl, about two drops of blood, into the reagent and mix.

STEP THREE
Step 3 - Results in three minutes

 Transfer it to the sensor strip. Press the button. Just three minutes later, you have your result.

Accuracy
LeadCare System vs. Atomic Absorption Spectroscopy performed at a major lead outreach and referral clinic/hospital
Number of Samples: 112
Slope: 1.07
Intercept: -0.57 µg/dl
Correlation coefficient: 0.97

Portable
Power source: 9V battery or AC adapter
Dimensions: 7.7 in x 4.2 in x 2.5 in. (19.6cm x 10.7cm x 6.4cm)
Weight: 14 oz

Specification
Test method:   Electrochemical with disposable sensors
Blood lead level range: 1.4 - 65 µg/dl
Blood sample volume: 50 µl
Test time: 3 minutes
Calibration: Electronic calibration button
Classification: Moderately complex under CLIA guidelines. Suitable for use in physician's office laboratory.

 

 

Theory of Anodic Strippimg Voltammetry (ASV)

ASV Method
Anodic Stripping Voltammetry is a highly precise, virtually interference-free method. 

  1. Whole blood is added to the reagent solution (Fig. 1), 
  2. Any lead present is released from the blood components (Fig. 2). 
  3. Now any lead in the reagent solution is concentrated (plated) onto a thin-film electrode during the plating step of the analysis cycle (Fig. 3).
  4. The plated lead is removed from the electrode by applying a stripping current (Fig. 4) and the  amount of lead is measured by integration of the electrical current released during this rapid electrochemical step. 

Anodic Stripping Voltammetry

 

Figure 1-ASV copy.JPG (9478 bytes)

 

Figure 2 - ASV copy.JPG (7909 bytes)

 

Figure 3 - ASV copy.JPG (7969 bytes)

 

Figure 4 - ASV copy.JPG (8609 bytes)
Figure 1 Figure 2 Figure 3 Figure 4

The current released during the stripping step, is a directly proportional to the amount of lead present in the blood sample.
Accurate Results
LeadCare® System vs. Atomic Absorption Spectroscopy performed at a major lead outreach and referral clinic/hospital
 
 Number of Samples

 112
 Slope

  1.07
 Intercept

 -0.57 µg/dl
 Correlation Coefficient

  0.97

 

Method Correlation
Results from the Model 3010B Lead Analyzer have shown close correlation with the widely accepted graphite furnace methodologies.  This is further supported by results from numerous proficiency surveys.

The Model 3010B provides the sensitivity you need for the detection of blood lead in childhood lead screening, industrial hygiene and occupational health monitoring programs.

The LeadCare system operates by fundamentally the same principal but uses a single-use electrode contained on a disposable slide.