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New and
exclusive IL-12 Family Members: Bioactive IL-39 and IL-Y
IL-12 family (IL-12, IL-23, IL-27, IL-35) proteinµéÀº ¸é¿ª ±â´ÉÀÇ Áß¿äÇÑ Á¶Àý ÀÎÀÚ·Î,
pre-inflammation°ú anti-inflammationÀ» ¸ðµÎ Á¶ÀýÇÒ ¼ö ÀÖ½À´Ï´Ù. R&D systems¿¡¼´Â »õ·Î¿î IL-2 family proteinÀÎ IL-39¿Í IL-Y Á¦Ç°À» »õ·Ó°Ô Ãâ½ÃÇß½À´Ï´Ù.See the data. |
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VSTMs: New
B7-Like Checkpoint Targets?
VSTMs´Â ±¸Á¶ÀûÀ¸·Î B7 protein°ú °ü·ÃÀÌ ÀÖÀ¸¸ç, ¸é¿ª Á¶Àý¿¡ °ü·ÃµÇ¾î ÀÖ½À´Ï´Ù. Lymphocyte¿¡¼ VSTM Á¦Ç°±ºÀÇ È¿°ú¸¦ È®ÀÎÇÑ data¸¦ È®ÀÎÇØ º¸¼¼¿ä. |
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CEACAMs:
Adhesion Molecules and Novel Targets for Cancer Therapies.
CEACAMs´Â Ig
superfamily¿¡ ¼ÓÇÏ´Â proteinÀ̸ç, ¿°Áõ, Ç÷°ü½Å»ý µî ´Ù¾çÇÑ »ý¹°ÇÐÀû ±â´É¿¡ °ü¿©ÇÕ´Ï´Ù. ¶ÇÇÑ ÃÖ±Ù¿¡´Â ¾Ï
Áø´Ü°ú Ä¡·á °¡´É¼ºÀ» È®ÀÎÇÏ´Â marker·Î °¢±¤¹Þ°í ÀÖ½À´Ï´Ù.
R&D systems¿¡¼´Â ¿¬±¸ÀÚÀÇ ÇÊ¿ä¿¡ µû¶ó ¼±ÅÃÇÒ ¼ö ÀÖ°Ô ´Ù¾çÇÑ CEACAMÀ»
Ãâ½ÃÇß½À´Ï´Ù. |
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Signal
Regulatory Proteins (SIRP)
SIRP alpha/CD47 signaling pathway´Â a myeloid-specific phagocytosis checkpointÀ̸ç
»õ·Î¿î Ä¡·á ´ë»óÀ¸·Î ÁÖ¸ñÀ» ¹Þ°í ÀÖ½À´Ï´Ù. ¾ÆÁ÷ ¹àÇôÁöÁö´Â ¾Ê¾ÒÁö¸¸ ÀÌ familyÀÇ ´Ù¸¥ proteinµéµµ ºñ½ÁÇÑ ±â´ÉÀ» °¡Áö°í ÀÖÀ» ¼ö
ÀÖ½À´Ï´Ù. |