cancer enews

Bio-Techne Newsletter | January 31, 2018

 

 

 

2¿ù Cancer Newsletter ¼Ò½Ä

Ø  Role for GDF-15 in Cancer

Ø  Webinar for Immune Checkpoint and Immune Responses

Ø  Parkinson¡¯s disease and Cancer

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Article

 

EMT and Invasion Induced by GDF-15 Signaling in Breast Cancer 
ÃÖ±Ù ³í¹®¿¡¼­(Peake et. Al.) growth differentiation factor 15 (GDF-15)´Â breast cancer¿¡¼­ insulin-like growth factor 1 receptor (IGF-1R)-FoxM1 pathway¸¦ ÅëÇØ epithelial mesenchymal transition (EMT) ¹× invasionÀ» À¯µµÇÑ´Ù´Â °ÍÀ» ÀÔÁõ ÇÏ¿´½À´Ï´Ù. Learn More!

 

gfral

 

A Role for GDF-15/GFRAL in Cancer? 
Growth differentiating factor 15 (GDF-15)
°¡ epithelial mesenchymal transition (EMT)¿Í invasion¿¡ Áß¿äÇÑ ¿ªÇÒÀ» ÇÑ´Ù´Â ¿¬±¸ °á°ú°¡ Áõ°¡ÇÏ°í ÀÖ½À´Ï´Ù. ÃÖ±Ù ³í¹®¿¡¼­ GFRALÀ» ºñ¸¸°ú insulin ÀúÇ×¼º¿¡ ´ëÇÑ GDF-15ÀÇ È¿°ú¸¦ ¸Å°³ÇÏ´Â receptor·Î È®ÀÎÇß½À´Ï´Ù. Bio-Techne¿¡¼­ Á¦°øÇÏ´Â GDF-15/GFRAL signaling pathway ¿¬±¸ ½Ã¾àÀ» È®ÀÎÇغ¸¼¼¿äLearn More!

 

myleod

 

Webinar: Targeting Myeloid-Derived Suppressor Cells 
Bio-Techne
¿¡¼­ metastatic castration resistant prostate cancer¿¡¼­ dual immune checkpoint blockade¿Í PI3K inhibitor Ä¡·áÀÇ È¿°ú¿¡ ´ëÇØ ³íÀÇ ÇÏ´Â Webinar¸¦ ÈÄ¿øÇÕ´Ï´Ù. (¹ßÇ¥ÀÚ Xin Lu). Watch Now!

 

monitor immune response

 

Webinar: Monitoring Immune Responses in Cancer Therapies: Avoiding the cytokine storm and other negative outcomes 
Bio-Techne
¿¡¼­ Dana Farber Cancer InstituteÀÇ Dr. Gordan J. Freeman ¿Í Memorial Sloan Kettering Cancer CenterÀÇ Dr. Michel Sadelain ÀÌ Âü¿©ÇÑ Science Webinar¸¦ ÈÄ¿øÇÕ´Ï´ÙWatch Now!

 

luminex hp cytokine 45 plex

 

New Luminex® High Performance Cytokine 45-Plex!
R&D systems
ÀÇ new Human XL Cytokine Discovery PanelÀº °æÀï»ç 3°÷ÀÇ Æгΰú side-by-side test¸¦ ÁøÇàÇß½À´Ï´Ù. 45°¡Áö analytesÁß ¿øÇÏ´Â targetÀ» ¼±ÅÃÇÏ¿© ¹Þ¾Æº¸¼¼¿äHuman XL Cytokine Discovery Panel 

 

RAS Signaling

 

Small Molecules for Cancer Immunology Research 
Cancer
¿¡ immunological response¿Í tumor¿¡ ÀÇÇÑ ÀÌ·¯ÇÑ responseÀÇ È¸ÇÇ´Â extracellular enzymes, receptors, ±×¸®°í intracellular signaling pathways¸¦ Æ÷ÇÔÇÏ´Â small moleculesÀÇ °³ÀÔ¿¡ ÀáÀçÀûÀÎ Æ÷ÀÎÆ®¸¦ Á¦°øÇÑ´Ù. TocirsÀÇ Cancer Immunology Á¦Ç°À» °Ë»öÇغ¸¼¼¿äCancer Immunology 

 

bioactive slit

 

Marked for Deletion: Parkin Ubiquitinylates HIF-1¥á to Stop Cancer 
ÃÖ±ÙParkinson¡¯s disease¿Í cancer »çÀÌ¿¡ ¿¹»óÄ¡ ¸øÇÑ ¿¬°üÀÌ ÀÖ´Ù´Â ¿¬±¸ °á°ú°¡ ¹ßÇ¥µÇ¾ú½À´Ï´Ù. E3 ubiquitin ligase È°¼ºÀ» ÅëÇØ ParkinÀº breast cancer ħÅõ¸¦ ¾ïÁ¦ÇÏ´Â HIF-1¥á¸¦ targeting ÇÕ´Ï´ÙLearn about the novel connection!

 

Bio-Techne at Upcoming Meetings

 

13th Biomarker Congress 2018
Manchester, UK, February 15-16, 2018

2018 American Association for Cancer Research
Chicago, USA, April 14-18, 2018 

British Society for Gene and Cell Therapy (BSGCT) Annual Conference 2018
London, UK, April 27, 2018 

25th Biennial Congress of the European Association for Cancer Research (EACR)
Amsterdam, Netherlands, June 30-July 3, 2018

 

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