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iPSC Heterogeneity Driven by Genetic Variation
ÃÖ±Ù Nature
Áö¿¡¼ Áٱ⠼¼Æ÷ ¿¬±¸ºÐ¾ßÀÇ È¥¶õ½º·± issue ÀÎ
cell line heterogeneityÀÇ ¿øÀο¡ ´ëÇØ , 711°³ÀÇ iPSC linces¸¦ °¡Áö°í À¯ÀüÀû Æò°¡¸¦ ¼Ò°³ÇÏ°í ÀÖ½À´Ï´Ù.
Donor¿Í sequence
variants°¡ ¾î¶»°Ô iPSCs¿¡ ¿µÇâÀ» ¹ÌÄ¡´ÂÁö ´õ ÀÚ¼¼È÷ ¾Ë¾Æº¸·Á¸é Ŭ¸¯ÇÏ¿© ±â»ç¸¦ È®ÀÎÇØ º¸¼¼¿ä.
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Increase the Reproducibility of iPSC
Differentiation
iPSCs¿¡¼ °üÂûµÈ donorÀÇ variability¿¡µµ ºÒ±¸ÇÏ°í, ¸î °¡Áö °£´ÜÇÑ
guidelines¸¦ µû¸£¸é
¼º°øÀûÀÎ differentiationÀÇ °¡´É¼ºÀ» ³ôÀÏ ¼ö ÀÖ½À´Ï´Ù. ÀÌ ±ÔÄ¢µéÀº ¸ðµç Áٱ⼼Æ÷ À¯Çü¿¡ Àû¿ëµÇ¸ç
ÀÌ ±â»ç¸¦ ÅëÇØ È®ÀÎÇÒ ¼ö ÀÖ½À´Ï´Ù.
Áö±Ý ¹Ù·Î È®ÀÎÇϼ¼¿ä!
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Verify Pluripotency in 5 Days - A Functional
Assay
Human Pluripotent Stem Cell Functional Identification Kit ´Â ´Ü 5ÀÏ ¸¸¿¡
iPSCsÀÇ tri-lineage differentiationÀ» È®ÀÎÇÒ ¼ö ÀÖ½À´Ï´Ù. ÀÌÁ¦ ´ç½ÅÀÇ ½ÇÇè¿¡¼ iPSC¸¦ »ç¿ëÇϱâ Àü¿¡ iPSCs°¡ ¿ÏÀüÈ÷ pluripotentÇÑÁö È®ÀÎÇÏ°í ½ÃÀÛÇϼ¼¿ä. ½±°Ô ÀÌ¿ëÇÒ ¼ö ÀÖ½À´Ï´Ù!
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A New Way to Monitor iPSC Differentiation
Proteome Profiler¢â ¿Í Luminex® Assays¸¦ »ç¿ëÇÏ¿© iPSC ºÐȸ¦ ¸ð´ÏÅ͸µ ÇÏ´Â ¹æ¹ý¿¡ ´ëÇÑ Webinar¸¦ º¸½Ç ¼ö ÀÖ½À´Ï´Ù. ÀÌ·¯ÇÑ platforms·Î »ý¼ºµÈ ÇÁ·ÎÆÄÀÏÀº ¼º°øÀûÀÎ differentiationÀ» ¿¹ÃøÇϴµ¥ »ç¿ëµÉ ¼ö ÀÖ½À´Ï´Ù. Áö±Ý ¹Ù·Î È®ÀÎÇØ º¸¼¼¿ä!
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Monitor iPSC Heterogeneity at the Single Cell
LevelP
ProteinSimpleÀÇ Milo¢â- Single-cell WesternÀ» »ç¿ëÇÏ¿© ´ç½ÅÀÇ iPSC¿¡¼ population heterogeneity ¶Ç´Â Â÷º°Àû ´Ü¹éÁú ¹ßÇöÀ» È®ÀÎÇØ º¸¼¼¿ä. ¼ö»ó °æ·Â¿¡ ºû³ª´Â ÀÌ ±â¼úÀº iPSC differentiationÀ» °ËÁõÇϴµ¥µµ »ç¿ëÇÒ ¼ö ÀÖ½À´Ï´Ù!
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Differentiate Your Stem Cells with TPPB from
Tocris!
TPPB´Â hESCs¸¦ Pdx-1À» ¹ßÇöÇÏ´Â pancreatic progenitor cells·Î ºÐȽÃÅ°´Â high-affinity, cell-permeable protein kinase C activatorÀÔ´Ï´Ù.
TocrisÀÇ stem cell
differentiation products¸¦ Áö±Ý ¸¸³ªº¸¼¼¿ä.
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Bio-Techne at
Upcoming Meetings
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ISSCR 2017
Annual Meeting¢â
Boston, MA, USA, June 14-17, 2017
Next Gen
Stem Cell Conference
Hartford, CT, USA, August 3-4, 2017
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