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Huntington's Disease (HD) Poster from Tocris
HD modeling iPSCs¿¡¼ HD pathology °ü·Ã ¼¼Æ÷ ³» signaling pathway¿¡ ´ëÇÏ¿© ¿¬±¸ÇÑ Æ÷½ºÅ͸¦ Tocris¿¡¼ È®ÀÎÇÏ½Ç ¼ö ÀÖ½À´Ï´Ù. (ÀúÀÚ: Annalena Wieland and Nicholas Allen, University of Cardiff)
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The Best E3 Ligase Enzymes for HD Research
E3 ligases´Â µ¹¿¬º¯ÀÌ Huntingtin (mHtt) ´Ü¹éÁúÀ» ºÐÇØÇÏ´Â È¿¼ÒÀ̸ç, E3 ligasesÀÇ ±â´ÉÀå¾Ö´Â HD¿¡ ±â¿©ÇÒ ¼ö ÀÖ½À´Ï´Ù.
Ubiquitin-related Á¦Ç°ÀÇ ¼±µÎÁÖÀÚÀÎ Bio-Techne's Boston Biochem¿¡¼ E3 ligases¸¦ ´Ù¾çÇÏ°Ô ¸¸³ªº¸½Ç ¼ö ÀÖ½À´Ï´Ù!
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Mouse Monoclonal Antibody for mHtt (Clone 1A771)
Huntingtin (mHtt)¿¡ ÀÇÇØ ¾ß±â µÈ Ubiquitin-positive neuronal intranuclear inclusions (NIIs)´Â Huntington's Áúº´¿¡¼ ½Å°æ Àå¾Ö ¹× º¯¼º¿¡ Áß¿äÇÑ ¿ªÇÒÀ» ÇÕ´Ï´Ù. Novus BiologicalsÀÇ anti-Huntingtin monoclonal antibody (clone 1A771)
´Â mHtt ´Ü¹éÁúÀ» ¼±ÅÃÀûÀ¸·Î È®ÀÎÇÒ ¼ö ÀÖ½À´Ï´Ù.
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A 769662-Induced AMPK Activation Reduces mHtt
Aggregates
HD pathologyÀÇ Å« Ư¡Àº mHTTÀÇ ÃàÀûÀÔ´Ï´Ù. ÃÖ±Ù ¿¬±¸¿¡ µû¸£¸é HD mouse model¿¡¼ À¯·¡ÇÑ STHdh cell¿¡¼ A 769662¿¡ ÀÇÇØ À¯µµ µÈ MAPKÀÇ È°¼ºÀº mTOR-independent autophagy¸¦ À¯µµÇϸç, ±× °á°ú·Î mHTTÀÇ ÃàÀûÀ» °¨¼Ò ½ÃŲ´Ù°í ÇÕ´Ï´Ù.
(ÀúÀÚ: Walteret al.)
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Luminex® Assays for Human Neuroscience Biomarkers R&D Systems´Â ½Å°æÅðÇ༺ Áúȯ °ü·Ã biomarkersÀÎ
GFAP,
Park5/UCH-L1, Park7/DJ-1, Tau, and Synuclein-¥áÀ» Human Luminex assay Á¦Ç°À¸·Î ÃÖ±Ù »õ·Î Ãâ½Ã ÇÏ¿´½À´Ï´Ù.
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Bio-Techne Travel Grants Available to ASCB 2016
R&D systems°¡ 2016³â 12¿ù 3ÀÏ-7ÀÏ °³ÃÖÇÏ´Â ASCB Âü¼®ÀÚ¸¦ À§ÇØ $1000 ¿©Çà °æºñ¸¦ Áö¿øÇØ µå¸³´Ï´Ù. Áö±Ý ½ÅûÇϼ¼¿ä! Apply Now!
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Bio-Techne at
Upcoming Meetings
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Cambridge
Stem Cell Institute 5th
International Symposium 2016
Cambridge, UNITED KINGDOM, July 18-19
Summer
Frontiers 2016 - Systems Biology of Innate Immunity 2016
Nijmegen, NETHERLANDS, September 7-9
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Nationale des Enseignants de Biologie Cellulaire 2016
Paris, FRANCE, September 22-24
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